Control Stress Levels and Boost Immunity
- A Conditionally Essential Amino Acid
- Vital in stress and illness
- Preserves protein synthesis, nitrogen balance and immunity
- Available in both capsule and powder form in an effective dosage
L-Glutamine helps support immune and digestive system health after periods of physical stress. L-Glutamine also helps to assist in muscle cell repair after exercise.
250 g Powder
Serving Size: 1 Tsp
- L-Glutamine 5 g
Key Feature: Fundamental amino acid
Suggested Use: Take 5 g in water or 8 capsules daily preferably on an empty stomach, or as directed by a qualified health care practitioner.
Cautions: Consult a health care practitioner prior to use if you are following a low protein diet.
Pregnancy/Nursing: Consult a health care practitioner
Source: Pharmaceutical synthesis
- Leaky gut
- Immune function
- Cellular growth and differentiation Muscular recovery
A key for many biological functions
L-glutamine is the most abundant free amino acid in the body. It is critical for many essential functions including the optimal operation of the kidneys, pancreas, gall bladder, liver, intestines and the brain. It is the most important amino acid for maintaining nitrogen balance. It supports the immune system and is a precursor for glutathione, one of the body’s most important antioxidants.
Although glutamine can be synthesized in the body, it becomes seriously depleted during conditions of stress such as injury, infection or strenuous exercise. During these conditions, glutamine is consumed faster than it is synthesized, and its shortage can lead to complications. Glutamine supplementation enhances the immune system by serving as fuel for immune cells. Glutamine supplementation also benefits muscles and the gastrointestinal system during conditions of stress. Glutamine’s ability to enhance growth hormone makes it a valuable supplement for athletic performance.
Many health benefits
Glutamine’s roles extend throughout the body and impact a wide range of health areas. AOR’s L-glutamine provides an effective dose of this important nutrient to avoid problematic depletions and enhance overall health.
Glutamine forms approximately one-fifth of the amino acid pool circulating in the human bloodstream. It is critical for a wide variety of essential functions, and is the most important of all amino acids in maintaining nitrogen balance within the body. Furthermore, it is a precursor for what is arguably the body’s most powerful endogenous antioxidant, glutathione
Glutamine becomes seriously depleted during the course of catabolic stress. Studies have found that glutamine levels can decrease by over 50% after a critical illness and may not recover to normal levels for over 21 days. During this time protein synthesis and nitrogen balance is disrupted and can contribute to systemic complications such as sepsis, malnutrition, mucosal breakdown, poor wound healing and multiple organ failure. While the average person is likely to consume approximately 10 grams of glutamine daily, a conservative estimate for the needs of someone in such a stressful state is 20-40 grams of glutamine per day.
Supporting the Digestive System
The intestinal tract and other portal-drained viscera account for approximately 40% of all the glutamine utilized by the whole body. The vast majority of this glutamine is converted into energy for use by the mucosa, the lining of the small intestine. This holds important implications for hospital patients placed on enteral nutritional support. Enteral diets enriched with glutamine are well-tolerated and alleviate many of the immunological aspects of multiple trauma patients as well as mitigating the extent of mucositis in post-chemotherapy patients.
The potency of glutamine has been examined for its possible applications against various types of cancer. Tumor growth is synonymous with a fervent consumption of glutamine which results in a decrease in the amount of glutamine available for glutathione production, which in turn results in the decreased numbers and activity of glutathione-dependent immune cells. In this situation, supplemental glutamine has been shown to revitalize immune cells by providing them with glutamine as fuel. In rats, glutamine supplementation was found to enhance the selectivity of anti-tumour drugs, protecting normal tissues while possibly sensitizing cancerous tissues to the drugs.
Infections cause significant changes in the distribution of glutamine among the organs of the body. Severe inflammatory infections are often referred to as sepsis, and during these periods, glutamine absorption is decreased. The intracellular glutamine pool becomes rapidly depleted, especially from the skeletal muscle and the lungs, and the major repository for the glutamine during these times of infection is the liver. The immune system is also a major consumer of glutamine during states of sepsis, and the cumulative effect of all of this glutamine redistribution is the reduced amount of glutamine available for other key cellular functions, including the production of antibodies and glutathione. Supplemental glutamine during these states of sepsis may alleviate this problem, and recent studies have confirmed this.
Growth Hormone and Athletic Health
The importance of growth hormone in overall health and vitality has been well-established for decades. Glutamine is one of the most effective and efficient natural growth hormone enhancers. Elevated levels of growth hormone have been linked to physical activity and exercise. Resistance training has a similar effect on endogenous glutamine reserves as sepsis, and the skeletal muscle amino acid pool begins to lose its all-important glutamine reserves. Scientists have now suggested that glutamine is a ‘conditionally essential’ amino acid and may need to be supplemented in the diet in certain stress situations.
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*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.