Help Your Body Cope With Stress

  • Mobilizes internal energy stores
  • Reduces the impact of stressful conditions
  • Activates whole-body defenses
  • Prevents the body from overreacting to a stressor

Ortho-Adapt is used in herbal medicine to help improve mental and/or physical performance after periods of mental or physical exertion and as a tonic to help relieve general debility and to aid during convalescence.

120-240 Capsules

Serving Size: 4 Capsules

  • Porcine Adrenal Gland Cortex 500 mg
  • Vitamin C 500 mg
  • Pantothenic acid (Pantethine, calcium D-Pantothenate) 200 mg
  • Licorice extract (Glycyrrhiza glabra, 25% glyzyrrhizin) 800 mg
  • Siberian ginseng extract (Eleutherococcus senticosus 10:1) 200 mg
  • Rhodiola rosea extract (3% rosavins, 1% salidroside) 150 mg
  • Ashwagandha extract (Withania somnifera 10:1)† 200 mg
  • Typically 2.5% withanolides, 0.1% sitoindosides

Key Features: Advanced Adaptogenic Formula

Suggested Use: Begin with 1 capsule daily with a meal, and increase to personal optimal level (up to 4 capsules daily) or as directed by a qualified health care practitioner. Consult a health care practitioner for use beyond 1 month.

Cautions: Consult a health care practitioner if you have diabetes, a liver disorder, any type of acute infection, if you are taking hormone replacement therapy, birth control pills or antidepressant medication, or if symptoms persist or worsen. Headaches, mild gastrointestinal disturbances (such as nausea), heart palpitations, or hyperactivity/insomnia may occur. Consumption with alcohol, other drugs or natural health products with sedative properties is not recommended. Do not use if you have Cushing’s syndrome, hypokalemia, high blood pressure, bipolar spectrum disorder, a kidney or cardiovascular disorder, if you are taking thiazide diuretics, cardiac glycosides, corticosteroids, stimulant laxatives or other medications which may aggravate electrolyte imbalance.

Pregnancy/Nursing: Do not take

Source: Multi-Sourced

Main Indications:

  • Adaptogen
  • Adrenal Support
  • Support during periods of stress

Complementary Products: Mag/Potassium Aspartates, L-Tyrosine, Ribogen Mg

Adaptogens and Stress

Many factors influence how the body responds to life’s challenges. Adaptogens are substances that mobilize internal energy reserves, preventing the body from overreacting to stress and thus avoiding, reducing, or delaying the burnout that follows periods of extreme stress. True adaptogens act by extending the phase of resistance, a state in which the body’s capacities are optimally mobilized to adapt to new challenges.

A Natural Solution for Coping with Stress

AOR’s Ortho-Adapt contains a carefully formulated blend of vitamins, nutrients and herbs with adaptogenic properties. These include pantethine (an active co-enzyme form of vitamin B5), Vitamin C, well-known botanicals like Rhodiola, Ashwagandha (Withania somnifera), Licorice (Glycyrrhiza glabra), Siberian “ginseng” (Eleutherococcus senticosus), and adrenal glandulars, providing superior support for the adrenal glands, which are key to the body’s stress coping abilities.

Many factors, such as healthy lifestyle habits as well as genetics and upbringing can influence how your body responds to life’s challenges. However, scientific research has also identified key botanicals and nutrients that can help you to rise to the demands of life.

Orthomolecules Essential to Adaptive Response

Pantethine is the active co-enzyme form of vitamin B5. Pantethine is converted by the body into a critical metabolic factor called coenzyme A (CoA). CoA in turn, plays an essential role in the biosynthesis of key adrenal hormones involved in the body’s release of energy reserves in response to stress. People who are deficient in vitamin B5 rapidly develop symptoms associated with burnout, including fatigue, listlessness, depression, headache, sleep disturbances, low immune function leading to more frequent colds and other infections, high blood pressure, and hypoglycemia.

Vitamin C has long been known to be critical to the ability of the adrenal glands to respond to stress. Vitamin C is involved in the biosynthesis of adrenal hormones, and concentrations of vitamin C in the healthy adrenal glands are higher than in any other part of the body except the brain. Human and animal studies have both shown that high-dose vitamin C supplementation can help to modulate the impact of stressful conditions, preventing immune suppression and buffering cortisol secretion.

Botanical Adaptogens

Rhodiola rosea is a well-studied adaptogen. It has a long history of use in the traditional medicine of Siberia for adaptation to the rigors of life on the tundras of North-Central Asia. More recently several scientific studies have documented the ability of standardized Rhodiola to enhance the body’s physical and mental work capacity and productivity under conditions of stress. Users find that Rhodiola is highly effective at helping with the psychological impact of stress, even as it enhances physical and mental endurance.

Ashwagandha (Withania somnifera) provides powerful support against overwhelming stress, but its effects are in many ways distinct from most other adaptogenic herbs. While most adaptogens primarily work by helping the body to mobilize and maintain the physiological response to stress, ashwagandha appears to work first and foremost by reducing the stress-related excesses of the alarmed nervous system.

Licorice (Glycyrrhiza glabra) is the source of the phytochemical glycyrrhizin, which acts to activate the receptors for key adrenal hormones (mineralocorticoids and glucocorticoids) involved in mobilizing energy reserves in response to stress. It also helps your body to keep these hormones in their more active forms, by inhibiting the enzymes that degrade adrenal hormones into less active forms.

Eleutherococcus senticosus, or “Siberian ginseng,” has powerful adaptogenic properties. It has been shown to enhance the immune system and improve physical performance. Eleutherococcus lacks the side effects observed in some users of Panax ginseng, which overexcites some people, and also has a more global beneficial effect on the immune system.

Adrenal Glandulars

Clinical experience has long endorsed the use of glandular extracts to support the activity of the target gland. Glandulars provide peptides and nutrient cofactors which are required for the gland to carry out its biological functions. To eliminate any risk of bovine spongiform encephalopathy (BSE), adrenal glandulars are porcine-sourced.

*Prices and product availability are subject to change without notice. All specials and promotions limited to stock on hand.

 *These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

Additional information


120 capsules, 240 capsules


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